This stable cell line, HPAC/JAK-Stat Pathway Firefly luciferase Reporter, originates from a moderately differentiated pancreatic ductal adenocarcinoma. It exhibits high levels of E-cadherin, CEA, and tight junction proteins, maintaining epithelial polarity and forming tight cell-cell contacts. Suitable for both 2D and 3D cultures, it's often employed as a model for early-stage pancreatic tumor behavior.