Gerber good start soothe formula is designed for babies experiencing excessive crying and colic, fussiness, gas, and mild spit-up. Gerber Good Start Infant Formula is the only formula with HMO* (human milk oligosaccarides) and probiotics. Research has shown that hmos support digestive health and the developing immune system. Gerber good start soothe formula has exclusive comforting probiotic L reuteri which has been clinically shown to reduce crying time in colicky babies. (Not from Human milk.)