Sterile Single-Use Containers. For mild to moderate dry eye including Lasik dryness (If used for post-operative [e.g. Lasik] dryness and discomfort, follow your eye doctor's instructions.). Refresh Brand is the no. 1 doctor recommended (Verispan's Physician Drug & Diagnosis Audit (PDDA), February 2000 - January 2005.). Long-lasting relief plus protection. No preservatives. Refresh Plus Lubricant Eye Drops does more than just soothe and relieve dry and irritated eyes. It also provides long-lasting moisturizing protection in a formula that contains many of the same healthy quantities as natural tears. Formulated for mild-to-moderate dry eye, Refresh Plus is preservative-free for sensitive eyes, and can be used as often as needed to provide 24-hour comfort. What Can Cause Dry Eye? Heat and air conditioning; Computer use and reading; Wind and sun; Certain medications; Natural aging process; Lasik procedures. Made in Ireland.