The Nunc™ Edge plate has a unique design that minimizes plate evaporation. A moat designed into the perimeter of the plate can be filled with 1.7 ml sterile H20 or media. Differential evaporation rates from the inside to the outside wells in each plate are known to generate variability in both biochemical and cell based assays. A volume loss as small as 10% concentrates media components and metabolites enough to alter cell physiology, in some cases, severely. The Edge plate design incorporates large evaporative buffer zones that eliminate well-to-well variability while dramatically reducing the overall plate evaporation rate to