Made of extra-tough nylon for powerful chewers weighing over 50 pounds, the Nylabone BIG Chew Knot Chew Toy is virtually indestructible for long-lasting enjoyment. BIG Chews encourage positive chewing habits, and the bristles raised during chewing promote clean teeth and help control plaque and tartar buildup. (Different dogs have different chewing styles and strengths, even within the same breed, so be sure to choose the correct chew size and type for your dog.)