*Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.; *Purity: >90%; *Tag Information: His tagged; *Species: Rabies virus (isolate Human/Algeria/1991) (RABV); *Seq: KFPIYTIPDKLGPWSPIDIHHLRCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDKSLHSRVFPSGNCSGITVSSTYCSTNHDYTIWMPENPRLETSCDIFTNSRGKRASKGSKTCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSDETKWCPPDQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSLRRLSHLRKLVPGFGKAYTIFNKTLMEAEAHYKSVQTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGHVLIPEMQSSLLQQHMELLESSVIPLMHPLADPSTVFKDGDEAEDFVEVHLPDVHKQVSGVDLGLPNWGKYVLLSAGTLIALMLIIFLMTCCRRVNRPKSTERSLGETGRKVSVTSQSGKVISSWESYKSGGETRR; *Accession#: P32550.1; P32550; *Uniprot Summary: Function: Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein G and thereby facilitate rabies virus entry into cells By similarity.Subunit structure: Homotrimer. Interacts with matrix protein By similarity.Subcellular location: Virion membrane; Single-pass type I membrane protein Potential. Post-translational modification: Glycosylated and palmitoylated by host. Glycosylation is crucial for glycoprotein export at the cell surface By similarity.Biotechnological use: Primary surface antigen capable of inducing and reacting with virus-neutralizing antibodies. Almost all human and veterinary vaccines are based on the functional aspects of the G protein.Miscellaneous: Arg-352 is highly involved in rabies virus pathogenicity. Its mutation dramatically attenuates the virus By similarity.Sequence ...