Compare to the active ingredients of NyQuil Cold and Flu. Calm your cold and flu symptoms so you can get the rest you need with Nighttime Cold and Flu. Each dose provides powerful relief for your minor aches and pains, fever, sore throat, sneezing, runny nose and cough. This cough, cold and flu medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) with ten percent alcohol to give you maximum strength, multi-symptom relief. In original flavor, each 30 mL dose helps relieve major flu symptoms for up to 6 hours so you can rest. Gluten free. Dosage cup included. For adults and children ages 12 and over.