Zwaste Replacement Breakthrough Indicators come in a pack of 1, 2, 5, 10, 25, or 50. Foxx Life Sciences' Breakthrough Indicator is qualitative colorimetric indicator for the exhaustion and end-of-service life of low-flow filters. The indicator changes its color to red when the filter needs to be replaced. The indicator is designed to provide real-time indication of the breakthrough of HPLC solvents vapors.. 0.39" diameter. 3.1" height. Pack of 10. . . Thomas 330-0915-OEM-TMS EZwaste Breakthrough Indicator, 0.39" Diameter, 3.1" Height, Pack of 10. Country of Origin : United States. Part Number : 1171W35PK. Pack of : 10.