The BeadBlaster 24 completely lyses, grinds and homogenizes a broad variety of biological samples. Even the most difficult and resistant samples are fully homogenized, often in 35 seconds or less. The stainless steel tube carrier subjects up to 24 samples to an optimized, high speed, 3D motion, producing high energy impacts between the samples and micro-beads to release cellular contents. After homogenization, samples can be centrifuged and the supernatant collected for further processing. Operating parameters are set and displayed digitally. To protect fragile, heat sensitive samples, the unit can be programmed to operate in shortened consecutive cycles with a rest period in between. Up to 50 such programs can be stored in memory. A transparent lid allows for visualization of samples, and features a mechanical lid lock that prevents opening when the BeadBlaster is in operation. A brushless motor reduces motor noise and provides maintenance free operation.