Minimizes evaporation, reduces cross-contamination and prevents spillage. A multilayer film consisting of a top pierce able clear polyethylene film and a white polypropylene sublayer with 96 circular areas void of adhesive. The white sublayer aids in the alignment of the film to the plate; alignment of opposing corner wells ensures that all 96-wells will be properly aligned. The adhesive-free zones are 9mm on center to facilitate multi-channel pipetting without adhesive fouling of pipet tips or robotic probes.