3M Empore high performance extraction disk plates are designed for solid phase extraction (SPE) of analytes from biological samples. Parallel sample processing allows 96 samples to be extracted in approximately one hour or less. Each well of the plate contains a standard density Empore particle-loaded membrane for efficient sample extraction. Elution can be accomplished in as little as 100-microliters with mobile phase or mobile phase compatible solutions for direct injection onto chromatographic systems. Extraction disk plates are ideal for sample preparation prior to LC/MS and other high throughput analytical instruments.