Cortizone 10 Cooling Relief Gel cools and soothes your skin on contact, and continues to relieve itch for hours. This fast absorbing bel contains the #1 doctor recommended ingredient you can buy without a prescription to relieve itching, plus Aloe and a unique cooling ingredient blend. Cortizone-10 Cooling Relief Gel provides lasting relief from itching and irritation due to insect bites, poison ivy, sunburn itch, rashes and allergic itch. Active Ingreidnets: Hydrocortisone 1%.