ProSignal ECL high contrast, high sensitivity X-ray film is specially formulated for an optimized balance of high sensitivity and low background. It is an excellent phototgraphic film for use with enhanced chemiluminescence (ECL) substrates for horseradish peroxidase (HRP) or alkaline phosphatase (AP). In addition to excellent sensitivity and contrast characteristics, it is also coated on both sides (double emulsion) for improved consistency and overall performance. The autoradiography film also works well for chemiluminescent or isotopic DNA and RNA methods, including Southern and Northern blotting and gel-shift assays (EMSA). The quality and price of this film make it the smart choice for life science research applications. Validated for use with ProSignal Pico, Dura, and Femto chemiluminescent substrates, the most advanced ECL reagents on the market (introduced in 2016) and other commerically available substrates. Packaged in lined, light-safe dispenser boxes that include an improved “lift off” cover. Film is packaged 100 sheets per box.