Product Description Advance to Healthier Gums and Stronger Teeth from Day 1 with Crest Pro-Health Advanced Gum Protection. This toothpaste contains ActivClean Crystals for stain prevention. It also provides Crestâ€s highest level of protection against plaque bacteria to keep gums healthy and provides longer lasting freshness. Ingredients Active Ingredient: Stannous Fluoride 0.454% (0.16% W/V Fluoride Ion) Inactive Ingredients: Glycerin, Hydrated Silica, Sodium Hexametaphosphate, Propylene Glycol, PEG-6, Water, Zinc Lactate, Flavor, Trisodium Phosphate, Sodium Gluconate, Sodium Lauryl Sulfate, Carrageenan, Sodium Saccharin, Stannous Chloride, Xanthan Gum, Titanium Dioxide, Mica, Blue 1. Instructions Adults and children 12 yrs. & older: apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening) or as recommended by a dentist.Make sure to brush all sensitive areas of the teeth. Do not swallow. Children under 12 yrs.: ask a dentist. Warnings Safety Warning: When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist. Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care. Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.