Keep 'em Happy with vet-formulated, chicken-flavored calming chews! Three effective calming ingredients support calm behavior and reduce stress in medium & large breed dogs fast, with no corn, no wheat, and no artificial flavors. Nobody's happy when your pet is feeling anxious or stressed, but Calming chews can help them relax. These tasty, bite-sized soft chews feature three effective active ingredients. The colostrum in Pet Naturals Calming chews is a special blend of milk proteins that promote calm behavior and stress relief in dogs of all breeds over 25 pounds. Colostrum can also help support brain health and function in pets of any age! Thiamine, also known as Vitamin B1, is an important vitamin that supports a balanced mood and sharp memory. As a part of our calming chews for dogs, thiamine offers calming benefits by helping the body manage stress and anxiety. L-theanine has unique calming and mood-balancing abilities: it stimulates the production of natural "feel-good" signals that are released in the brain to help support anxiety, sleep, digestion, and more! L-theanine supports relaxation without drowsiness. Pet parents report seeing positive effects for four hours or longer! Pet Naturals Calming chews for medium & large breed dogs are not a sedative, and won't dim your pet's shine. If your furry friend is feeling extra stressed, it's OK to give them another chew (or two!) to keep them calm. Calming chews can be given to your pet daily or simply as needed. Only 3 chews/day for dogs over 100 pounds!